研究発表

論文・誌上発表 (生物影響分野) 

タイトル 著者 資料名 巻号,頁
On radiation-induced aging: accelerated or premature aging. Wada, T., T. Kinugawa and S. Tanaka 2022 Radiat. Prot. Dosim. 198(13-15), 1155-1159.
Combined analysis of cancer incidence and lifespan in mice exposed to chronic low dose rate radiation. Kinugawa, T., T. Wada, Y. Manabe, F. Sato, S. Tanaka 2022 Radiat. Prot. Dosim. 198(13-15), 1160-1164.
Premature menopause and obesity due to oocyte loss in female mice chronically exposed to low dose-rate γ-Rays. Nakamura, S., I. B. Tanaka III, J. Komura and S. Tanaka 2022 Radiat. Prot. Dosim. 198(13-15), 926-933.
Experimental studies at the IES on the biological effects of chronic low dose-rate radiation exposure in mice. Tanaka, I. B. 2022 Radiat. Prot. Dosim. 198(13-15), 985-989.
Low dose-rate radiation-specific alterations found in a genome-wide gene expression analysis of the mouse liver. Fujikawa, K., T. Sugihara, S. Tanaka, I. Tanaka, S. Nakamura, M. N. Murano, H. Murano J. Komura 2022 Radiat. Prot. Dosim. 198(13-15), 1165-1169.
Comparison of the proliferative responses of hematopoietic stem cells exposed to low dose rate radiation in vivo and ex vivo. Hirouchi, T. 2022 Radiat. Prot. Dosim. 198(13-15), 1025-1029.
Adaptive response in mice continuously irradiated with low dose-rate radiation Sugihara, T., H. Murano, K. Fujikawa, I. Tanaka, J. Komura 2022 Radiat. Prot. Dosim. 198(13-15), 1196-1199.
Life Span, Cause of Death and Neoplasia in B6C3F1 Mice Exposed In Utero to Low- and Medium-Dose-Rate Gamma Rays Ignacia B. Tanaka III, Rei Nakahira, Jun-ichiro Komura, Satoshi Tanaka 2022 Radiation Research 198(6), 553-572
Frequencies of Chromosome Aberrations are Lower in Splenic Lymphocytes from Mice Continuously Exposed to Very Low-Dose-Rate Gamma Rays Compared with Non-Irradiated Control Mice Atsushi Kohda, Takuo Toyokawa, Tomoyuki Umino, Yoshiko Ayabe, Ignacia Braga Tanaka III, Jun-ichiro Komuraa 2022 Radiation Research 198(6), 639-645
Adverse effects of chronic low dose-rate gamma-ray exposure ameliorated by environmental enrichment in mice. Takai, D., A. Abe, H. Miura, I.B. Tanaka, M. Saito, J. Komura 2021 Int. J. Rad. Res. 19(3), 543-550.
Effects of continuous in utero low- and medium-dose-rate gamma-ray exposure on fetal germ cells Rei Nakahira, Yoshiko Ayabe, Ignacia Braga-Tanaka,III, Satoshi Tanaka, Jun-ichiro Komura 2020 Radiat. Res. 195(3), 235-243
Life-shortening effect of chronic low-dose-rate irradiation in calorie-restricted mice Kazumi Yamauchi, Tetsuya Ono, Yoshiko Ayabe, Shun'ichi Hisamatsu, Manabu Yoneya, Yuki Tsutsumi and Jun-ichiro Komura 2019 Radiat. Res. 192, 451-455
Minimum environmental enrichment is effective in activating antitumor immunity to transplanted tumor cells in mice Daisaku Takai, Akiko Abe, Heita Miura, Satoshi Tanaka and Jun-ichiro Komura 2019 Exp. Anim. 68(4), 569-576.
Diverse functions of the thrombopoietin receptor agonist romiplostim rescue individuals exposed to lethal radiation. Yamaguchi, M., T. Hirouchi, H. Yoshioka, J. Watanabe and I. Kashiwakura 2019 Free Radic. Biol. Med. 136, 60-75.
Chronic exposure to gamma irradiation at low dose rates accelerates blood pressure decline associated with aging in female B6C3F1 mice. Takai, D., A. Abe, and J. Komura 2019 Int. J. Radiat. Biol. 95(3),347-353
Effects of N-acetylcysteine on life shortening induced by chronic low dose-rate gamma-ray exposure in mice. Yamauchi, K., Y. Tsutsumi, K. Ichinohe, M. Yoneya, J. Komura, T. Ono, and K. Tanaka 2019 Int. J. Radiat. Res. 17(1),67-73
Funding for radiation research: past, present and future.. Cho, K., T. Imaoka, D. Klokov, T. Paunesku, S. Salomaa, M. Birschwilks, S. Bouffler, A. L. Brooks, T. K. Hei, T. Iwasaki, T. Ono, K. Sakai, A. Wojcik, G. E. Woloschak, Y. Yamada and N. Hamada 2019 Int. J. Radiat. Biol. 95(2), 1-25.
Experimental studies on the biological effects of chronic low dose-rate radiation exposure in mice: overview of the studies at the Institute for Environmental Sciences. Braga-Tanaka, I., S. Tanaka, A. Kohda, D. Takai, S. Nakamura, T. Ono, K. Tanaka and J. Komura 2018 Int. J. Radiat. Biol. 94(5), 423-433.
Effects of continuous gamma-ray exposure in Utero in B6C3F1 mice on gestation day 18 and at 10 weeks of age. Gulay, K. C. M., I. Braga-Tanaka, J. Komura and S. Tanaka 2018 Radiat. Res. 189(4), 425-440.
Screening of biomarkers for liver adenoma in low-dose-rate γ-ray-irradiated mice. Sugihara, T., S. Tanaka, I. Braga-Tanaka, H. Murano, M. Nakamura-Murano and J. Komura 2018 Int. J. Radiat. Biol. 94(4), 315-326.
The thrombopoietin mimetic romiplostim leads to the complete rescue of mice exposed to lethal ionizing radiation. Yamaguchi, M., T. Hirouchi, K. Yokoyama, A. Nishiyama, S. Murakami and I. Kashiwakura 2018 Scientific reports 8(1), 10659.
Radioprotective activity of blackcurrant extract evaluated by in vitro micronucleus and gene mutation assays in TK6 human lymphoblastoid cells. Yamamoto, A., T. Hirouchi, S. Kawamorita, K. Nakashima, A. Sugiyama and Y. Kato 2017 Genes and Environment 39, 22.
Preservation of chromosomal integrity in murine spermatozoa derived from gonocytes and spermatogonial stem cells surviving prenatal and postnatal exposure to γ-rays in mice. Watanabe, H., A. Kohda, J. Komura and H. Tateno 2017 Mol. Reprod. Dev. 84(7), 638-648.
Differences in sustained alterations in protein expression between livers of mice exposed to high-dose-rate and low-dose-rate radiation. Nakajima, T., B. Wang, T. Ono, Y. Uehara, S. Nakamura, K. Ichinohe, I. Tanaka, S. Tanaka, K. Tanaka and M. Nenoi 2017 J. Radiat. Res. 58(4), 421-429.
Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair-dependent and independent mechanisms. Nakamura, T., K. Murakami, H. Tada, Y. Uehara, J. Nogami, K. Maehara, Y. Ohkawa, H. Saitoh, H. Nishitani, T. Ono, R. Nishi, M. Yokoi, W. Sakai and K. Sugasawa 2017 Genes Cells 22(4), 392-405.
Pathology of serially sacrificed female B6C3F1 mice continuously exposed to very low-dose-rate gamma rays. Tanaka, I., J. Komura and S. Tanaka 2017 Radiat. Res. 187(3), 346-360.
High mutation levels are compatible with normal embryonic development in Mlh1-deficient mice. Fan, X., Y. Li, Y. Zhang, M. Sang, J. Cai, Q. Li, T. Ozaki, T. Ono and D. He 2016 Radiat. Res. 186(4), 377-384.
Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE(-/-) Alzheimer's mouse model. Kempf, S. J., D. Janik, Z. Barjaktarovic, I. Tanaka, S. Tanaka, F. Neff, A. Saran, M. R. Larsen and S. Tapio 2016 Oncotarget 7(44), 71817-71832
CCL11-induced eosinophils inhibit the formation of blood vessels and cause tumor necrosis. Xing, Y., Y. Tian, T. Kurosawa, S. Matsui, M. Touma, T. Yanai, Q. Wu and K. Sugimoto 2016 Genes Cells 21(6), 624-638.
Expression analysis of radiation-responsive genes in human hematopoietic stem/progenitor cells. Tsujiguchi, T., T. Hirouchi, S. Monzen, Y. Tabuchi, I. Takasaki, T. Kondo and I. Kashiwakura 2016 J. Radiat. Res. 57(1), 35-43.
急性骨髄性白血病につながる造血細胞および組織の放射線応答. 小嶋 光明, 廣内 篤久 2016 放射線生物研究 51(1), 34-56.
Mitigative effects of a combination of multiple pharmaceutical drugs on the survival of mice exposed to lethal ionizing radiation. Hirouchi, T., K. Ito, M. Nakano, S. Monzen, H. Yoshino, M. Chiba, M. Hazawa, A. Nakano, J. Ishikawa, M. Yamaguchi, K. Tanaka and I. Kashiwakura 2015 Current pharmaceutical biotechnology 17(2), 190-199.
Acceleration of atherogenesis in ApoE-/- mice exposed to acute or low-dose-rate ionizing radiation. Mancuso, M., E. Pasquali, I. Tanaka, S. Tanaka, A. Pannicelli, P. Giardullo, S. Pazzaglia, S. Tapio, M. J. Atkinson and A. Saran 2015 Oncotarget 6(31), 31263-31271.
Dose and dose-rate effects of ionizing radiation: a discussion in the light of radiological protection. Ruhm, W., G. E. Woloschak, R. E. Shore, T. V. Azizova, B. Grosche, O. Niwa, S. Akiba, T. Ono, K. Suzuki, T. Iwasaki, N. Ban, M. Kai, C. H. Clement, S. Bouffler, H. Toma and N. Hamada 2015 Radiat. Environ. Biophys. 54(4), 379-401.
Effects of chronic low dose-rate gamma irradiation on the anti-tumor activity and chemokine systems in mice. Takai, D., A. Todate, K. Ichinohe and J. Komura 2015 Journal of Radiobiology 2(2), 24-29.
Experimental approach to prezygotic chromosome screening using only a single pair of gametes in mice. Watanabe, H., A. Kohda and H. Tateno 2015 The Journal of Reproduction and Development 61(6), 511-518.
Effects of Chronic Low Dose-rate Gamma Ray Irradiation in Mice. Tanaka, I., S. Tanaka and S. Nakamura 2015 Nova Science Publishers pp.135-153
Dose and dose-rate response of lymphocyte chromosome aberrations in mice chronically irradiated within a low-dose-rate range after age adjustment. Tanaka, K., K. Satoh and A. Kohda 2014 Radiat. Prot. Dosimetry 159(1-4), 38-45.
Abnormality in Wnt signaling is causatively associated with oxidative stress-induced intestinal tumorigenesis in MUTYH-null mice. Isoda, T., Y. Nakatsu, K. Yamauchi, J. Piao, T. Yao, H. Honda, Y. Nakabeppu and T. Tsuzuki 2014 Int. J. Biol. Sci. 10(8), 940-7.
Chromosomal gain aberrations predominate in murine myeloid leukemia induced by continuous exposure to low-dose γ-irradiation. Hirouchi, T., S. Tanaka, I. Tanaka and K. Tanaka 2014 Radiation Emergency Medicine 3(1), 35-44.
Long-lasting radioprotective effects of a combination of pharmaceutical drugs on the survival of mice exposed to lethal ionizing radiation. Yamaguchi, M., T. Hirouchi, M. Nakano, S. Monzen, H. Yoshino, M. Chiba, J. Ishikawa, A. Nishiyama, S. Murakami, K. Ito and I. Kashiwakura 2014 Radiation Emergency Medicine 3(1), 50-55.
Cancer prevention by adult-onset calorie restriction after infant exposure to ionizing radiation in B6C3F1 male mice. Shang, Y., S. Kakinuma, K. Yamauchi, T. Morioka, T. Kokubo, S. Tani, T. Takabatake, Y. Kataoka and Y. Shimada 2014 Int. J. Cancer 135(5), 1038-47.
Total body 100-mGy X-irradiation does not induce Alzheimer’s disease-like pathogenesis or memory impairment in mice. Wang, B., K. Tanaka, B. Ji, M. Ono, Y. Fang, Y. Ninomiya, K. Maruyama, N. Izumi-Nakajima, N. Begum, M. Higuchi, A. Fujimori, Y. Uehara, T. Nakajima, T. Suhara, T. Ono and M. Nenoi 2014 J. Radiat. Res. 55, 84-96.
血清成分にみられる低線量率放射線の影響. 杉原 崇 2014 放射線生物研究 49(1), 85-97.
In vivo partial bystander study in a mouse model by chronic medium-dose-rate gamma-ray irradiation. Sugihara, T., H. Murano, M. Nakamura and K. Tanaka 2013 Radiat. Res. 179(2), 221-231.
Dose-rate effects and dose and dose-rate effectiveness factor on frequencies of chromosome aberrations in splenic lymphocytes from mice continuously exposed to low-dose-rate gamma-radiation. Tanaka, K., A. Kohda and K. Satoh 2013 J. Radiol. Prot. 33(1), 61-70.
Low Amount Expression of Ku 70 Protein Related to Radiation-induced Chromosome Instability and Radiosensitivity in Normal Lymphocytes, and Leukemia and Lymphoma Cell Lines. Tanaka, K., T. S. Kumaravel and N. Gajendran 2013 Ind. J. Sci. Technol. 6(2), 3981-3989.
p-Terphenyl Derivatives from the Mushroom Thelephora aurantiotincta Suppress the Proliferation of Human Hepatocellular Carcinoma Cells via Iron Chelation. Norikura, T., K. Fujiwara, T. Yanai, Y. Sano, T. Sato, T. Tsunoda, K. Kushibe, A. Todate, Y. Morinaga, K. Iwai and H. Matsue 2013 J. Agric. Food. Chem. 61(6), 1258-1264.
低線量率放射線連続照射による生体内分子シグナルの解明. 杉原 崇 2013 放影協ニュース 4月号.
Increased gamma-H2A.X intensity in response to chronic medium-dose-rate gamma-ray irradiation. Sugihara, T., H. Murano and K. Tanaka 2012 PloS one 7(9), e45320.
High Incidence of Loss of RARA-PML Chimeric Gene of Acute Myelocytic Leukemia M3 with Simple or Complex 15;17 Translocation. Tanaka, K., T. Shintani, M. Minamihisamatsu, T. Kyo and N. Kamada 2012 Ind. J. Sci. Technol. 5(9), 3229-3240.
Complex 8;21 Chromosome Translocations formed by Two Step Mechanism and Simple 8;21chromosome Translocation without AML1 Gene Involvement in Acute Myelocytic Leukemia. Tanaka, K., M. Minamihisamatsu, T. Kyo and N. Kamada 2012 Ind. J. Sci. Technol. 5(3), 2240-2252.
Higher Involvement of Subtelomere Regions for Chromosome Rearrangements in Leukemia and Lymphoma and in Irradiated Leukemic Cell Line. Tanaka, K., N. Gajendran, H. Asaoku, T. Kyo and N. Kamada 2012 Ind. J. Sci. Technol. 5(1), 1801-1811.
Immunohistochemical detection of possible cellular origin of hepatic histiocytic sarcoma in mice. Ohnishi, K., S. Tanaka, Y. Oghiso and M. Takeya 2012 Journal of clinical and experimental hematopatholog 52(3), 171-177.